Whole Exome Sequencing WES Panel Test in Ahmedabad
Whole Exome Sequencing WES Panel Test cost in Ahmedabad.
Whole exome sequencing or WES which also includes clinical exom sequencing is a molecular test performed to detect genes for various genetic diseases including hereditary diseases, cancers, hematological disorders, dysplasia, and many more.
What is WES test : The complete genomic information within individual is known as the whole genome. Exons are the genome’s protein-coding regions and are collectively known as the exome. Whole Exome Sequencing assay is a widely used method that involves sequencing the complete coding region of the genome. It is designed to examine all the coding regions and splice junctions of the genome. Exome sequencing using exome enrichment can efficiently identify coding variants (SNVs/Indels/CNVs)across a broad range of applications, including population genetics, genetic disease, and cancer studies.
When looking for an answer, something to explain the underlying cause of a disease, researchers often turn to the genome. With more than 3.2 billion bases in the human genome, the first and most financially viable step is to narrow the search to portions most likely to be informative. To do this, researchers can extract specific portions of the genome for sequencing with target enrichment panels. Picking the right panel is key to collecting quality, informative data. Researchers have two options at this stage: small and targeted panels (Clinical exome) or whole exome panels. Clinical exome sequencing is including in whole exome sequencing so its better to get done WES at same price.
- Test cost price in Ahmedabad : Rs 20000
- Report time : 20-30 Days
- What is required : Blood sample which can be collected at our lab or at home / hospital / office.
WES test is designed for deeper coverage & precise diagnosis – Performed on Most powerful sequencer- Illumina NovaSeq 6000 system.
- NV/Indels & CNV: Artificial Intelligence & machine learning powers improved SNV/Indels & CNV detection
- 7 Gb-10 Gb Sequencing data : Uniform coverage with a mean depth of >80-100X. 7Gb-10Gb data/sample
- Comprehensive panel design : Covers >20,250 Genes with protein-coding regions, several non-coding variants & intron-exon boundaries. Covers all 16,659 base pairs & 37 genes of the mitochondrial genome
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Spiked coverage over noncoding regions that are known to carry pathogenic or likely pathogenic variants enhances our exome panel’s discovery power : High Performance Exome Built on Advanced and Proven Technology
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Maximum coverage : Complete new design that maximizes coverage of clinically relevant regions from the ClinVar database while including updated coverage of protein-coding regions from CCDS, RefSeq and GENCODE.
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Mitochondrial genome: Covers all 16,659 base pairs & 37 genes of the mitochondrial genome. Sequencing depth optimized for Heteroplasmy detection.
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36.5 Mb target region: This exome panel spans a 36.5 Mb target region of the human genome. The panel delivers excellent enrichment performance for more uniform coverage, lower GC bias, meaning this panel can help detect complex targets containing high, or low, levels of GC content.
Why Us ? : Most commercially available exome panels cover nearly all gene-coding sequences in the genome But, one key and critical differentiating factor is how deeply they cover specific genes. While some whole-exome panels focus on providing particularly deep coverage over genes that are relevant to cancer development, inherited disorders, or other such conditions, this panel provides deep coverage over all genes that have been linked to clinical phenotypes, enabling translational research on a wide range of conditions.
